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Fun Science FRIEDay – Fasting Fights Cancer?

Happy Fun Science FRIEDay to everyone. FSF is back and with a new name!

After a brief hiatus to sort out some legal issues regarding the title of FSF, and a trip to the World Cup, I am hopefully back into the swing of providing you with mostly weekly, fun, and interesting science facts!

Up this week is cancer, and what we as a species are doing to kick its ass! … along w/ the involuntary help of the Mus musculus species.

Relatively recent work by Dr. Longo, of the University of Southern California, and his colleagues, has shown that a simple dietary adjustment may help combat the negative influence of chemotherapy and age on immune cell function! In short, their findings suggest that fasting, yes you heard right, FASTING, may provide benefits for cancer patients and the elderly by replenishing stem cells in the blood.

 

Conceptualization of the influence prolonged fasting has to promote stem cell regeneration and reverse immunosuppression. (Photo credit: Cheng et al. 2014)

Conceptualization of the influence prolonged fasting has to promote stem cell regeneration and reverse immunosuppression. (Photo credit: Cheng et al. 2014)

Dr. Longo explains, “We show that prolonged fasting periods cause a major reduction in white blood cell number followed by its replenishment after refeeding. We discovered that this effect, which may have evolved to reduce energy expenditure during periods of starvation, is able to switch stem cells to a mode able to not only regenerate immune cells and reverse the immunosuppression caused by chemotherapy, but also rejuvenate the immune system of old mice.”

So remember, the next time someone you know is complaining about how hungry they are, tell them to take a chill pill, and keep on fighting cancer! ;)

You can view the full article of this work in the journal Cell.