Amidst all the hysteria surrounding the seemingly unstoppable COVID-19, we bring you a story of a fish without blood. In 1928 a biologist sampling off the coast of Antarctica pulled up an unusual fish. It was extremely pale (translucent in some parts), had large eyes and a long toothed snout, and somewhat resembled a crocodile (it was later named the “white crocodile fish). Unbeknownst at the time, but the biologist had just stumbled on a fish containing no red blood pigments (hemoglobin) and no red blood cells – he iron-rich protein such cells use to bind and ferry oxygen through the circulatory system from heart to lungs to tissues and back again. The fish was one of sixteen species of what is now commonly referred to as icefishes that comprise the family Channichthyidae, endemic around the Antarctic continent.
Scientists (and sci-fi fans) have to varying degrees been discussing the concept of suspended animation for years; the idea that the biological functions of the human body can somehow be put on “pause” for a prescribed period of time while preserving the physiological capabilities. If you’ve ever watched any sci-fi movie depicting interstellar travel you have probably seen some iteration of this concept as a way to get around the plot conundrum of the vastness of space and space travel times, relative to natural human aging and human life span. The basic principle of suspended animation already exists within the natural world, associated with the lethargic state of animals or plants that appear, over a period, to be dead but can then “wake-up” or prevail without suffering any apparent harm. This concept is often termed in different contexts: hibernation, dormancy, or anabiosis (this last terms refers to some aquatic invertebrates and plants in scarcity conditions). It is these real-world examples that likely inspire the human imagination of the possibilities for suspended human animation. The concept of suspended human animation is more commonly viewed through the lens of science fiction (and interstellar travel), however, the shift of this concept from scientific fiction to science reality has a more practical human application.
The Emperor of all Maladies is how Siddhartha Mukherjee, an Indian-born American physician and oncologist, aptly described cancer. Cancer, this scourge of mankind going back as far as 4,600 years ago when it was identified by the Egyptian physician Imhotep (the first in recorded history). Cancer takes one of the most successful traits of complex eukaryotes, cell division, and weaponizes it in unchecked cellular growth; some even consider cancer to be a more evolved form of cell division. This ailment has plagued humanity, and baffled physicians for centuries as they attempt to tackle the seemingly impossible, discover a cure for cancer.
Inception, a clever movie starring Leonardo DiCaprio where the premise of the story is to sneak into a person’s subconscious and implant an idea or a memory whilst they sleep. When the person awakes from their slumber they cannot distinguish the implanted memory from their own. It makes for blockbuster cinematography, but the practical concept is quite frightening to think about: the ability to artificially implant memories inches closer to the prospect of reality distortion.
Why does life exist? Its an age old question that has been debated for centuries with popular hypotheses crediting celestial interference, a primordial soup, or a colossal stroke of luck. However, a relatively recent and provocative hypothesis suggests luck has nothing to do with it, and that instead, life is an inevitable consequence of physics.
The author of the concept, Jeremy England – professor of biophysics at MIT, suggests, “the origin and subsequent evolution of life follow from the fundamental laws of nature and should be as unsurprising as rocks rolling downhill.”
The process of blood transfusions, started in the late 19th century and perfected in the early 20th century, were a big advancement in modern medicine and the treatment of human health. Part of the improvements in this procedure was the discovery of the various blood types in humans, and how that affects how the immune system responds to and “accepts” blood transfusions. Recently, researchers from the University of British Columbia may have found a reliable way to use a bacterial enzyme from the human gut to convert any type of blood into type O – which is compatible with nearly everyone.
Animation of red blood cells (Photo credit: meghanmecrazy)
Life has unbelievably complex and diverse strategies to ensure survival. Organisms are able to go dormant during unfavorable conditions, and resuscitate once the environment becomes ideal again. This can play out over relatively short time periods such as when animals hibernate, or over longer periods where organisms can go into stasis, e.g. reviving bacteria from 250 million year old salt crystals.
Researchers in Russia recently thawed out permafrost sediment frozen for the past 42,000 years, and revealed once frozen and now living nematodes. Yes you heard that correctly, worms birthed and subsequently frozen during the Pleistocene (42,000 years earlier) were just resurrected in the 21st century. Frankenstein, eat your heart out.
Eophasma jurasicum, a fossilized nematode. (Photo credit: Ghedoghedo)
Our lives are a blip in the space time continuum. As a result, it can seem that the Earth is relatively static, with many of the large scale dynamic changes that shape our sphere largely unnoticeable to us occurring on geological time-scales. One such change is the movement of landmasses on earth, better known as plate tectonics.
Earth’s landmasses are not static but in constant flux. The Earth’s lithosphere (formed by the crust and the upper part of the mantle) is broken up into a number of tectonic plates that move relative to each other at varying speeds, “gliding” over a viscous asthenosphere. There is still ongoing debate about what force or forces causes this movement, but whatever the forces are they can also cause the plates to rupture, forming rifts, and potential leading to the development of new plate boundaries. When this happens landmasses break-up and new continents forms; this is currently happening in the East African Rift in southwestern Kenya.
View of East African Rift in Kenya from space (Photo credit: Google Earth. Data SIO, NOAA, US Navy, NGA, GEBCO).
Cancer is a tricky disease. It comes in many varieties and can pop-up anywhere in the body seemingly at random. The somewhat cryptic nature of this disease can make diagnosis difficult; this can be frustrating because most cancers are treatable if diagnosed early. Thats what makes this most recent breakthrough all the more exciting; a method to detect cancer through a single blood test!
The blood test is called CancerSEEK and its speculated that it would cost less than 500 USD, which is comparable to or lower than other screening tests. CancerSEEK, is a single blood test that was shown to detect 8 types of common cancer (ovary, liver, stomach, pancreas, esophagus, colorectum, lung, and breast) and helps identify the location of the cancer.
One of the most basic things that we learn when growing up is that water can exist in 3 different states of matter: as a gas (water vapor), as a liquid (water… water), and as a solid (ice). This basic and fundamental concept has recently been turned upside down as scientist have discovered that water might also exists in a fourth state; liquid water it appears might actually come in two different states. A collaborative team of researchers led by Dr. Laura Maestro at Oxford University, found that the physical properties of water changed their behavior between 50 and 60℃ potentially changing to a second physical state of water.
(Photo credit: Pixabay/Public Domain Pictures via CC0 Public Domain)