Fun Science FRIEDay – Embryonic Gene Editing

The world we currently live in would have seemed like science fiction to humans in the not to distant past. Everyday more and advancements transform sci-fi dreams into reality. Most recently gene editing of human embryos has been birthed into the realm of possibility (cheesy pun intended!). In theory gene editing embryos could allow you to choose preferential traits in your soon to be human flesh-blob. That level of ability does not currently exist, but the latest developments in gene editing are still pretty astonishing.

Eggs before gene editing (left), and eggs after gene editing and already undergoing cell division (right)
(Photo credit: Ma et al. 2017)

In a recent study scientists took a human embryo and edited a dangerous mutation from the genes of that embryo; human reality, meet science fiction. Scientists at Oregon Health and Science University, with colleagues in California, China and South Korea, edited embryos, fixing a mutation that causes a common heart condition that can lead to sudden death later in life. The biggest hurdles were producing embryos in which all cells, not just some, were mutation-free, while also avoiding creating unwanted extra mutations during the process. The researchers found that when gene-editing components were introduced with sperm to the egg before fertilization, the success of the process was markedly different from previous approaches. If embryos with the repaired mutation were allowed to develop into babies, they would not only be disease-free but would also not transmit the disease to their descendants.

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Happy Fun Science FRIEDay – Change you DNA… One Step at a Time!

It’s around about this time of year when people begin to question their New Year’s resolutions to commit to better health. You know what I am talking about. Right after NYE the number of people at the gym swells to an unholy number of hopeful fitness do-gooders. Yet without fail, by the end of the month the gym population begins to stabilize back to its pre New Year’s resolution numbers. But maybe, just maybe, this article will convince you to stick with your commitment to better health, change your DNA regarding your approach to fitness, and keep on exercising! Because exercise, as a new study has found, does just that. Exercise changes the shape and functioning of our genes, an important step on the way to improved health and fitness!

Photo credit: precisionnutrition.com

Photo credit: precisionnutrition.com

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