Fun Science FRIEDay – Virus be good!

“The era of the oncolytic virus is… here.” Stephen Russell, Cancer researcher and haematologist at the Mayo Clinic in Rochester, Minnessota

…. and let me be the first to welcome our new virus overlords!

 Viral-based cancer therapy: T cells (orange) are recruited to attack malignant cells (purple). (Photo credit: Dr. Andrejs Liepins/SPL)

Viral-based cancer therapy: T cells (orange) are recruited to attack malignant cells (purple). (Photo credit: Dr. Andrejs Liepins/SPL)

Last week the US Food and Drug Administration (FDA) made a decision that received little fanfare, but has huge implications for modern medicine and how we approach cancer treatment in the US. That decision? The FDA granted their approval for a genetically engineered virus to be used to treat cancer. That virus was the herpesvirus called talimogene laherparepvec, and its use is for the treatment of melanoma lesions in the skin and lymph nodes. This huge decision makes it the first oncolytic virus to receive market approval and could pave the way for more oncolytic viruses to enter the “market.”

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